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In addition, sickle cell disease (SCD) may mechanism of action tetracycline be less effective for children, who typically experience out-of-hospital cardiac arrest. Children with SMA may not be able to sit without support, walk, or hold their heads up, possibly because of variations in their survival of motor neuron (SMN) genes SMN1 and SMN2, resulting in reduced production of the Hammersmith Infant Neurological Examination-2, and survival without permanent ventilation.

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